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Description

Lei C, Niu X, Wei J, Zhu J, Zhu Y

System x c mediated uptake of extracellular cystine serves as the principal method by which many cancer cells acquire cellular cystine [10]

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Cyclophosphamide and ifosfamide, both used in cancer treatment, undergo metabolism to produce acrolein, which is a significant concern because it induces oxidative stress and can lead to hemorrhagic cystitis (120)